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Instruction for Prednisone
Contraindications to the use of Prednisone
What is Prednisone
Pharmachologic effect. Prednisone has anti-allergic and anti-inflammatory effects. It is 4-5 times more active than cortisone and 3-4 times hydrocortisone when applied orally. In contrast, the drug causes less retention of sodium and water in the body and only slightly increases the release of potassium.
Indications. Prednisone is used for rheumatism, gouty, infectious polyarthritis, allergic diseases (bronchial asthma, urticaria, etc.), certain blood diseases (acute leukemia, infectious mononucleosis), as well as in dermatology (pemphigus, neurodermatitis, eczema, etc.) and in ophthalmology (Keratitis, conjunctivitis of non-infectious etiology, etc.). Prednisone is prescribed for Addison's disease, chorea, etc.
Application. Prednisone is administered internally at 0.025-0.05 g per day in 4 applications. When switching from cortisone to prednisone give 1 / 4-1 / 5 doses of the cortisone used before. To eliminate acute symptoms of the disease prednisone is prescribed up to 0.015-0.02 g per day, then the dose is reduced to 0.01-0.005 g per day. The duration of treatment is individualized depending on the course of the disease and the therapeutic effectiveness of the drug. During treatment, patients are shown nutrition, rich in proteins. When infectious diseases simultaneously with prednisone prescribe antibiotics and other chemotherapeutic agents, with the risk of thrombosis - anticoagulants. If it is necessary to use prednisone for a long time in large doses, simultaneously give methylandro-stentiol 0,025-0,05 g per day in order to protect against the enhanced decay of the protein. During treatment with prednisone, it is necessary to monitor systematically the picture of blood, weight, blood pressure, sugar content in the blood and the state of the nervous system.
Possible complications. When applying prednisone, there may be swelling, alkalosis, increased blood sugar, agitation, insomnia, mild hirsutism, sometimes amenorrhea, osteoporosis. With prolonged administration of the drug, oppression of the adrenal cortex function is possible; the sudden cancellation of it can cause a sharp exacerbation of the inflammatory process in patients with infectious arthritis.
Contraindications. Prednisone is contraindicated in hypertensive disease, Cushing's disease, pregnancy, cardiac decompensation, acute endocarditis, psychosis, nephritis, osteoporosis, peptic ulcer and duodenal ulcer, recent surgery, syphilis, tuberculosis (in the absence of specific treatment), severe forms of sugar Diabetes, in old age.
Form of issue. Tablets of 0,005 g in a package of 100 pieces.
Storage. With precaution (List B). Prednisone is supplied from the Polish People's Republic.
Prednisone is a medicine offered in the form of pills or in the form of a liquid. It is prescribed to people with low levels of corticosteroids, hormones that regulate the adrenal glands that suppress inflammation in the body and protect against disorders such as arthritis and multiple sclerosis.
This drug should be taken with food or milk to reduce irritation of the intestine and prevent ulcers. When taking prednisone in liquid form, it is recommended to mix it with juices, apple puree or other liquid food.
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